Angela Langdon

This study shows psilocybin enhances choice selection in uncertain contexts by altering cortical processing to prioritize positive information over previous actions.

This study shows that reducing Grin2a in adolescent rat dopamine neurons leads to psychosis-like behaviors and dopamine signaling abnormalities relevant to schizophrenia.

This study shows chronic ethanol exposure impairs cognitive flexibility and striatal decision signals in male rats, with specific changes in neural representations of actions and outcomes.

This study shows that hippocampal lesions affect dopamine neuron firing patterns during a reward prediction task, contrasting with the role of the orbitofrontal cortex.

This study uses fMRI and PPI analysis to show that striatal connectivity with lateral orbitofrontal cortex and CM-Pf thalamus differs in their association with speed and quality of reversal learning in humans.

This study shows that dorsal striatal choline levels are linked to reversal learning performance in humans, supporting the role of the cholinergic system in behavioural flexibility.