Alejandro Torrado Pacheco

This study shows psilocybin enhances choice selection in uncertain contexts by altering cortical processing to prioritize positive information over previous actions.

This study shows that reducing Grin2a in adolescent rat dopamine neurons leads to psychosis-like behaviors and dopamine signaling abnormalities relevant to schizophrenia.

This study shows acute psilocybin improves cognitive flexibility in rats by enhancing switching between learned strategies, with effects mediated by 5HT2A receptors.

The paper demonstrates that sleep enables downward firing rate homeostasis, which is distinct from upward homeostasis and occurs during sleep rather than wake.

This study shows that V1 neurons maintain stable firing rates during expected light-dark transitions but respond to unexpected changes, with correlations during natural vision being more informative than individual rates.

This study shows that Shank3 loss disrupts homeostatic plasticity and circuit stability, which can be rescued by lithium, suggesting a therapeutic target for Shankopathies.