Author

Jared T. Ahrendsen

Beth Israel Deaconess Medical CenterORCID 0000-0002-9309-6544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew ThorntoniD· 1 shared Arne GennerichiD· 1 shared Caroline M. MebaneiD· 1 shared Cody L. DuntoniD· 1 shared David VanDerwayiD· 1 shared Demirkan Besim Gursel· 1 shared Greta Wodarcyk· 1 shared Guillermo Antonio AmeeriD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Andrew ThorntonORCID

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2 papers

Recent·Most cited

Leveraging chromatin packing domains to target chemoevasion in vivo

Jane Frederick, Ranya K. A. Virk, I Chae Ye, Luay Matthew Almassalha, Greta Wodarcyk, David VanDerway, Ruyi Gong, Cody L. Dunton, Tiffany Kuo, Karla Medina, Margarita Loxas, Jared T. Ahrendsen, Demirkan Besim Gursel, Paola Carrillo Gonzalez, Rikkert J. Nap, , Vadim Backman

This study develops a physics-based model linking chromatin organization to chemoevasion, identifies TPR compounds that enhance chemotherapy efficacy in ovarian cancer.

Proceedings of the National Academy of Sciences · Jul 22, 2025Peer-reviewedBiophysics

Genotype and defects in microtubule-based motility correlate with clinical severity in KIF1A Associated Neurological Disorder

Lia Boyle, Lu Rao, Simranpreet Kaur, Xiao Fan, Caroline M. Mebane, Laura Hamm, Andrew Thornton, Jared T. Ahrendsen, Matthew P. Anderson, John Christodoulou, Arne Gennerich, Yufeng Shen, Wendy K. Chung

This study links KIF1A variants to clinical severity in KAND by analyzing transport defects and protein dysfunction.

Human Genetics and Genomics Advances · Jan 30, 2021Peer-reviewedGenetic & Genomic Medicine