Adham Safieddine

This study shows that MTPAP loss causes mitochondrial RNA processing defects, leading to type I interferon signaling upregulation through mt-dsRNA accumulation.

The paper predicts cell cycle phases from microscopy data using a variational auto-encoder with auxiliary tasks, and provides a new annotated dataset.

This study examines how mRNA localization to P-bodies changes during the cell cycle, revealing that mRNA dynamics in P-bodies are not solely linked to translation status but are regulated by RNA features and RBPs.

FISH-quant v2 is a modular tool for analyzing smFISH images, enabling detection, segmentation, quantification, and visualization of RNA localization at the single-cell level.