Author

Alexandre Pierga

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Adham SafieddineiD· 1 shared Alice LepelleyiD· 1 shared Antria SavvidouiD· 1 shared Blaise Didry‐BarcaiD· 1 shared Carola Hedberg Oldfors· 1 shared Claire LovoiD· 1 shared Dominique Barbieri-WeilliD· 1 shared Gittan KollbergiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Adham SafieddineORCID

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2 papers

Recent·Most cited

Epigenetic profile drives accurate survival prediction in breast cancer via a multi-omics machine learning model

Guillaume Mestrallet, Alexandre Pierga, Paul Frémont

This paper develops a multi-omics machine learning model to predict breast cancer survival, finding that epigenetic features are the strongest predictors.

Peer Community Journal · Jul 22, 2026Peer-reviewedCancer Biology

Loss of MTPAP disrupts mitochondrial RNA processing causing upregulation of type I interferon signalling

Alexandre Pierga, Yan de Souza Angelo, Adham Safieddine, Marie‐Noëlle Benassy, Blaise Didry‐Barca, Marie Rozen, Luís Seabra, Claire Lovo, Sylvie Bannwarth, Sandra Lacas‐Gervais, Gittan Kollberg, Carola Hedberg Oldfors, Antria Savvidou, Dominique Barbieri-Weill, Yanick Joseph Crow, Alice Lepelley

This study shows that MTPAP loss causes mitochondrial RNA processing defects, leading to type I interferon signaling upregulation through mt-dsRNA accumulation.

bioRxiv · May 7, 2026 · PreprintCell Biology