Aaron T. Smith

Single-cell imaging of the lytic phage life cycle in bacteria

This study uses time-lapse imaging to analyze phage infection dynamics in bacteria, revealing heterogeneity and its impact on phage fitness.

The structure of the full catalytic cycle of Vibrio cholerae NFeoB

This paper determines the X-ray crystal structures of V. cholerae NFeoB to elucidate its full catalytic cycle and functional features.

The Pseudomonas aeruginosa Membrane Histidine Kinase BqsS/CarS Directly Senses Environmental Ferrous Iron (Fe2+)

This study characterizes PaBqsS, an iron-sensing membrane histidine kinase, showing it directly binds Fe2+ and its ATPase activity is stimulated by Fe2+.

The response regulator BqsR/CarR controls ferrous iron (Fe2+) acquisition in Pseudomonas aeruginosa

This study identifies PaBqsR as a regulator of Fe2+ acquisition in P. aeruginosa by directly binding Fe2+ and controlling the feo operon.

Identification of an intrinsically disordered region (IDR) in arginyltransferase 1 (ATE1)

This study identifies an intrinsically disordered region in mouse ATE1, contrasting with yeast ATE1, and suggests its role in facilitating complex formation with tRNAArg.

Structural Determinants of Vibrio cholerae FeoB Nucleotide Promiscuity

This study identifies structural determinants of FeoB nucleotide promiscuity in Vibrio cholerae by analyzing crystal structures and thermodynamics.