Rinky D. Parakra

MInt-HDX improves protein-ligand docking by integrating HDX-MS data with machine learning and physics-based methods to enhance docking accuracy and ligand pose ranking.

This study identifies an intrinsically disordered region in mouse ATE1, contrasting with yeast ATE1, and suggests its role in facilitating complex formation with tRNAArg.

The paper introduces PyHDX, a tool for analyzing HDX-MS data to compute residue-level Gibbs free energy across protein conditions and homologues.

The paper investigates the structural dynamics of SctV, a component of the Type III translocase export gate in E. coli, revealing its conformational changes and interactions with chaperones and ATPase.