Fangliang Zhang

This study shows trypsin can remove N-terminal arginine residues in an exopeptidase-like manner, potentially biasing proteomic analyses.

This study identifies ER stress and nitroso-redox imbalance as key drivers of NEPC progression and shows that NO supplementation reduces tumor burden and metastasis in mice.

This study shows NDR1/2 kinases regulate cell polarization and motility via Cdc42 and Pard3 signaling in human fibroblasts, affecting wound healing.

This study shows that Ate1 induces cell death via a mitochondria-dependent pathway, independent of cytosolic degradation pathways and mitochondrial ROS.

This study identifies an intrinsically disordered region in mouse ATE1, contrasting with yeast ATE1, and suggests its role in facilitating complex formation with tRNAArg.