Zuzana Sumbalova Koledova

S100A4+ stromal cells are required for functional nipple development and successful nursing

This study shows that S100A4+ cells are essential for nipple development and successful nursing, as their depletion leads to nursing defects and litter loss.

Adeno-Associated Virus Co-Precipitation with Extracellular Vesicles for Genome Editing in Rodent Embryo

This paper describes a method to co-isolate AAV with extracellular vesicles for efficient genome editing in rodent embryos, achieving higher viability and targeting efficiency compared to traditional purification methods.

Contractile fibroblasts are recruited to the growing mammary epithelium to support branching morphogenesis

The paper identifies a transient population of contractile fibroblasts in the mouse mammary gland that support branching morphogenesis through recruitment from the fat pad.

FSP1 stem/progenitor cells are essential for TMJ growth and homeostasis

This study identifies FSP1-expressing cells as essential stem/progenitor cells in the TMJ condyle, showing their role in growth, homeostasis, and cartilage maintenance through Wnt signaling regulation.

Fibroblast-induced mammary epithelial branching depends on fibroblast contractility

This study shows fibroblast contractility is essential for inducing mammary epithelial branching through physical contact and signaling pathways involving YAP and ERK.

FGF signaling dynamics regulates epithelial patterning and morphogenesis

The paper investigates how FGF signaling dynamics influence epithelial morphogenesis by analyzing mammary organoids and using mathematical modeling.

3D cell culture models demonstrate a role for FGF and WNT signaling in regulation of lung epithelial cell fate and morphogenesis

This study uses 3D cell culture models to investigate the role of FGF and WNT signaling in lung epithelial cell fate and morphogenesis, revealing their effects on organoid formation and differentiation.

A pleiotropic role for FGF signaling in mammary gland stromal fibroblasts

This study identifies FGF signaling's role in mammary fibroblasts, showing it regulates proliferation, migration, ECM production/remodeling, and epithelial branching.