Anas Rabata

The paper generates immortalized AT2 cell lines from healthy and IPF lungs that maintain key biological features in 2D and 3D cultures, providing a platform for lung disease research.

This study identifies LPCAT1 as a critical regulator of AT2 cell renewal and lipid metabolism in IPF, showing that reactivating LPCAT1 can mitigate lung fibrosis.

This study identifies NAMPT as a key regulator of alveolar progenitor cell function in IPF, showing that its activation restores homeostasis and reverses fibrosis in mice.

This study uses 3D cell culture models to investigate the role of FGF and WNT signaling in lung epithelial cell fate and morphogenesis, revealing their effects on organoid formation and differentiation.