Protonated Structure of EmrE Reveals C-terminal Tail Gating Mechanism
Ashley Hiett, Benjamin D. Harding, Merissa Brousseau, Owen A. Warmuth, Collin G. Borcik, Chao Wu, Eva-Maria Uhlemann, Claudia C. Cornilescu, Grace E. Reichert, Chad M. Rienstra, Katherine A. Henzler‐Wildman
The paper reports the high-resolution structure of protonated EmrE, revealing how the C-terminal tail occludes the transport pore to prevent proton leak.
bioRxiv · Jun 1, 2026 · PreprintBiophysics