Author

Merissa Brousseau

University of Wisconsin–MadisonORCID 0000-0003-0555-7177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:E. coli· 1 Assay:protein structure· 1

Frequent Co-Authors

Katherine A. Henzler‐WildmaniD· 2 shared Ashley HiettiD· 1 shared Benjamin D. HardingiD· 1 shared Chad M. RienstraiD· 1 shared Chao WuiD· 1 shared Claudia C. CornilescuiD· 1 shared Collin G. BorcikiD· 1 shared Da TengiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Katherine A. Henzler‐WildmanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 1, 2026

Protonated Structure of EmrE Reveals C-terminal Tail Gating Mechanism

Ashley Hiett, Benjamin D. Harding, Merissa Brousseau…·Katherine A. Henzler‐Wildman

The paper reports the high-resolution structure of protonated EmrE, revealing how the C-terminal tail occludes the transport pore to prevent proton leak.

DOI 10.64898/2026.05.28.728512

protein structureexperimental assay

𝕏 PostBluesky

BiophysicseLifePeer-reviewedJul 7, 2025

The C-terminus of the multi-drug efflux pump EmrE prevents proton leak by gating transport

Merissa Brousseau, Da Teng, Nathan E. Thomas…·Katherine A. Henzler‐Wildman

This paper shows that the C-terminal tail of EmrE prevents proton leak by acting as a secondary gate, which is unlocked by substrate binding.

2 citations

E. coliexperimental assay

𝕏 PostBluesky