Author

Benjamin R. Gilbert

University of Illinois Urbana-ChampaignORCID 0000-0002-9344-5521Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Troy A. BrieriD· 3 shared Zaida Ann Luthey-SchulteniD· 3 shared Zane R. ThornburgiD· 3 shared Angad P. MehtaiD· 2 shared Enguang FuiD· 2 shared John I. GlassiD· 2 shared Yang-le GaoiD· 2 shared Andrew K. MaytiniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBiophysics

Troy A. BrierORCID

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Author profile →

3 papers

Recent·Most cited

BiophysicsCellPeer-reviewedMar 9, 2026

✦ In-depth digest

Bringing the Genetically Minimal Cell to Life on a Computer in 4D

Zane R. Thornburg, Andrew K. Maytin, Jiwoong Kwon…·Zaida Ann Luthey-Schulten

A hybrid 4D whole-cell simulation of the minimal bacterium JCVI-syn3A integrates spatial reaction-diffusion, metabolism, polymer chromosome dynamics, and division across a complete 105-minute cell cycle.

44 citationstop 1%

bacteria (other)E. coli

𝕏 PostBluesky

BiophysicsThe Journal of Physical Chemistry BPeer-reviewedDec 22, 2025

Assembly of Macromolecular Complexes in the Whole-Cell Model of a Minimal Cell

Enguang Fu, Zane R. Thornburg, Troy A. Brier…·Zaida Ann Luthey-Schulten

The paper integrates the assembly of 21 macromolecular complexes into a whole-cell kinetic model of JCVI-syn3A, improving efficiency and consistency with experimental data.

2 citations

E. colimetabolomics

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintOct 23, 2025

Unraveling the Transcriptional Landscape within a Minimized Bacterium via Comparative Analysis

Troy A. Brier, Jason E. Cournoyer, Benjamin R. Gilbert…·Zaida Ann Luthey-Schulten

This study compares transcriptomes of two minimized bacteria to understand gene expression patterns and highlights limitations of bioinformatics alone.

1 citation

E. colibulk RNA-seq

𝕏 PostBluesky