Author

Jason E. Cournoyer

University of Illinois Urbana-ChampaignORCID 0000-0002-0385-0110Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:long-read sequencing· 2 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Angad P. MehtaiD· 2 shared Christopher J. FieldsiD· 2 shared Gavin JohniD· 2 shared John I. GlassiD· 2 shared Karrie C. Goglin· 2 shared Sujata Shivakumar· 2 shared Tiana Mamaghani· 2 shared Troy A. BrieriD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Angad P. MehtaORCID

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2 papers

Recent·Most cited

Full-length transcriptomics and proteomics reveal how genome minimization reshapes gene expression in synthetic bacteria

Enguang Fu, Troy A. Brier, Jason E. Cournoyer, Sage Glass, Yang-le Gao, Yanbao Yu, Zane R. Thornburg, Karrie C. Goglin, Gavin John, Tiana Mamaghani, Sujata Shivakumar, Abner T. Apsley, Christopher J. Fields, Angad P. Mehta, John I. Glass, Zan Luthey-Schulten

The paper characterizes RNA and protein expression in synthetic bacteria Syn1.0 and Syn3A, showing genome minimization alters gene expression and resource allocation.

bioRxiv · Sep 10, 2026 · PreprintSynthetic Biology

Unraveling the Transcriptional Landscape within a Minimized Bacterium via Comparative Analysis

Troy A. Brier, Jason E. Cournoyer, Benjamin R. Gilbert, Sage A. Glass, Yang-le Gao, Yanbao Yu, Zane R. Thornburg, Karrie C. Goglin, Gavin John, Tiana Mamaghani, Sujata Shivakumar, Christopher J. Fields, John I. Glass, Angad P. Mehta, Zaida Ann Luthey-Schulten

This study compares transcriptomes of two minimized bacteria to understand gene expression patterns and highlights limitations of bioinformatics alone.

bioRxiv · Oct 23, 2025 · PreprintSynthetic Biology