Author

Carolina López

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0002-9357-3486Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:human· 1

Frequent Co-Authors

Alejandro J. VilaiD· 3 shared Guillermo BahriD· 2 shared Matteo Dal PeraroiD· 2 shared Robert A. BonomoiD· 2 shared A Pedro GonzáleziD· 1 shared Alessio PrunottoiD· 1 shared César A. AriasiD· 1 shared Christina Maria Anna Pia SchuhiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

Alejandro J. VilaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Functional export of NDM-7 to outer membrane vesicles in Klebsiella pneumoniae compromises imipenem and cefiderocol activity

A Pedro González, Valeria E Quiroz, Katherine Soto, Christina Maria Anna Pia Schuh, Lorena Díaz, César A. Arias, Alejandro J. Vila, Jose Manuel Munita, Carolina López

This study shows that NDM-7 carbapenemase is exported to outer membrane vesicles in Klebsiella pneumoniae, enabling extracellular antibiotic degradation and conferring resistance to imipenem and cefiderocol.

bioRxiv · Jun 29, 2026 · PreprintMicrobiology

OXA beta-lactamases from Acinetobacter spp. are membrane-bound and secreted into outer membrane vesicles

Lucia Capodimonte, Fernando Teixeira Pinto Meireles, Guillermo Bahr, Robert A. Bonomo, Matteo Dal Peraro, Carolina López, Alejandro J. Vila

This paper identifies membrane-bound OXA beta-lactamases in Acinetobacter spp. and shows they are secreted into outer membrane vesicles, contributing to antimicrobial resistance.

mBio · Dec 13, 2024Peer-reviewedMicrobiology

Specific protein-membrane interactions promote the export of metallo-β-lactamases via outer membrane vesicles

Carolina López, Alessio Prunotto, Guillermo Bahr, Robert A. Bonomo, Lisandro J. González, Matteo Dal Peraro, Alejandro J. Vila

The paper shows that specific protein-membrane interactions enhance the export of metallo-β-lactamases into outer membrane vesicles in Gram-negative bacteria.

Antimicrobial Agents and Chemotherapy · Jul 26, 2021Peer-reviewedMolecular Biology