Camaron R. Hole

This study shows that neutrophils protect against cryptococcosis by limiting CCR2-dependent monocyte-driven immunopathology, even without affecting fungal burden.

The paper shows that reactive oxygen species (ROS) drive lethal inflammation in response to a C. neoformans chitosan-deficient mutant, highlighting ROS-dependent neutrophil-mediated immunopathology.

This study shows that growing Cryptococcus neoformans in unbuffered YNB media improves gene deletion efficiency using short homology arms.

This paper identifies CD4+ T cells and their cytokines IFNγ, TNF, and IL-23 as critical for vaccine-mediated protection against Cryptococcus neoformans, with protection retained after vaccination even with CD4+ T cell depletion.