Lethal streptococcal infection is associated with widened lymph node bottlenecks
Linya Xia, Karthik Hullahalli, Xingyu Tian, Chen Yuan, Fei Pan, Hongjie Fan, Matthew K. Waldor, Zhe Ma
This study shows that lethal Streptococcus suis serotype 2 infection in mice is driven by widened lymph node bottlenecks and the virulence factor suilysin, leading to systemic bacterial spread.
bioRxiv · Jan 29, 2025 · PreprintMicrobiology