Author

Andrés Posbeyikian

University of East AngliaORCID 0000-0002-9368-6659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:plant (other)· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Jiorgos KourelisiD· 3 shared Mauricio P. ContrerasiD· 3 shared Sophien KamouniD· 3 shared AmirAli ToghaniiD· 2 shared Hsuan PaiiD· 2 shared Jogi MadhuprakashiD· 2 shared Alessia Munzone· 1 shared Bastien BissaroiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPlant Biology

Jiorgos KourelisORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Pik NLR pair accumulates at the plasma membrane as a hetero-oligomeric sensor-helper immune protein complex prior to activation

Hsuan Pai, Mauricio P. Contreras, Jose Salguero Linares, Daniel Lüdke, Andrés Posbeyikian, Jiorgos Kourelis, Sophien Kamoun, Clémence Marchal

The paper shows that the rice NLR pair Pik-1 and Pik-2 forms a hetero-oligomeric complex at the plasma membrane in the resting state before effector activation.

bioRxiv · Dec 2, 2025 · PreprintPlant Biology

Functional insights into a peculiar tetra-modular LPMO from the human pathogen Enterobacter cloacae

Koyel Bardhan, Saumashish Mukherjee, Theruvothu Madathil Vandhana, Alessia Munzone, Andrés Posbeyikian, Sacha Grisel, Lal Duhsaki, Jean‐Guy Berrin, Bastien Bissaro, Jogi Madhuprakash

This study functionally characterizes a tetra-modular LPMO from Enterobacter cloacae, revealing its chitin-cleaving activity and structural features involving copper coordination.

bioRxiv · Jul 4, 2025 · PreprintBiochemistry

A hierarchical immune receptor network in lettuce reveals contrasting patterns of evolution in sensor and helper NLRs

Hsuan Pai, Toshiyuki Sakai, Andrés Posbeyikian, Raoul Frijters, Yu Sugihara, Mauricio P. Contreras, Jiorgos Kourelis, Hiroaki Adachi, Sophien Kamoun, AmirAli Toghani

The paper analyzes NLR evolution in lettuce and related species, finding that sensor NLRs evolve faster than helper NLRs and that sensor diversification is linked to helper dependency.

bioRxiv · Feb 25, 2025 · PreprintPlant Biology

A disease resistance protein triggers oligomerization of its NLR helper into a hexameric resistosome to mediate innate immunity

Jogi Madhuprakash, AmirAli Toghani, Mauricio P. Contreras, Andrés Posbeyikian, Jake Richardson, Jiorgos Kourelis, Tolga O. Bozkurt, Michael Webster, Sophien Kamoun

This study determines the structure of sensor-activated NbNRC2 using cryo-EM, revealing a hexameric resistosome and highlighting structural changes during NLR activation.

Science Advances · Nov 6, 2024Peer-reviewedPlant Biology