Yu Sugihara

This study identifies how two distinct NLR receptors recognize tobamovirus movement proteins, revealing convergent evolution and distinct recognition mechanisms.

The paper identifies the sex chromosome in white Guinea yam and describes a miRNA-mediated sex determination system involving a 1.2-Mb inversion and a W-specific microRNA gene.

This study identifies a novel wheat immune receptor pair, R3NLR and R3AK, where R3AK executes cell death through its 4-helical bundle domain, revealing a non-canonical NLR/MLKL resistance mechanism.

The paper examines the evolutionary divergence of the RAR1-SGT1 chaperone complex in leptosporangiate ferns, identifying key residues that dictate binding specificity and revealing a stepwise evolutionary pathway.

The paper introduces SNI, a framework to identify atypical protein assemblies, and applies it to NLRs, finding an undecameric assembly in NRC7 orthologs.

AlphaFold 3 oligomer models separate paired plant NLRs: helpers score higher pTM and form funnel-shaped resistosomes unlike sensors, including some rice pairs lacking integrated-domain annotations.

The paper identifies two candidate genes involved in sex determination in the dioecious wild yam Dioscorea tokoro using whole-genome sequencing and genetic analysis.

The paper shows that NRC3 evolved to resist suppression by a nematode effector, revealing a new type of gene-for-gene interaction between pathogens and host immune receptors.

The paper analyzes NLR evolution in lettuce and related species, finding that sensor NLRs evolve faster than helper NLRs and that sensor diversification is linked to helper dependency.

This study shows how the helper NLR NRC2 converts from a homodimer to a higher-order oligomer upon activation by the sensor NLR Rx, revealing the molecular mechanism of plant immune activation.

The paper shows how functional divergence in NRC3 variants shapes the genetic architecture of the NLR network in solanaceous plants, leading to subfunctionalization and increased immune system complexity.

The paper shows that the rice NLR-ID receptor Pii2 indirectly recognizes the fungal effector AVR-Pii by dissociating Pii2 from host Exo70 proteins, revealing a novel mechanism of pathogen recognition.

This paper identifies GF14h as the causal gene for low-temperature seed germination in rice and demonstrates its utility in breeding for direct seeding in cold climates.

The paper identifies horizontal mini-chromosome transfers in clonal blast fungus lineages, showing genetic exchange between host-associated isolates.

The paper introduces updated pipelines for MutMap and QTL-seq that are faster, easier to use, and more accessible via bioconda.