BioinformaticsbioRxivPreprint
Single-Cell Analysis of the 3D Topologies of Genomic Loci Using Genome Architecture Mapping
Lonnie R. Welch, Catherine Baugher, Yingnan Zhang…·Ana Pombo
The paper introduces a single-cell analysis of Genome Architecture Mapping (GAM) data, revealing intercellular heterogeneity in 3D chromatin topology and developing a geometric model for nuclear structure.