Philippe Bouloc

The paper uses Ribo-seq to show IsrR represses gabT translation during iron limitation in S. aureus, preventing TCA cycle precursor accumulation and metabolic imbalance.

This paper identifies RsaE, a non-coding RNA, as a regulator of psm transcript stability and biofilm properties in MRSA, showing its role in toxin expression, biofilm maturation, and dissemination.

This study identifies RsaOI, an sRNA in S. aureus, that links cell wall stress responses to galactose metabolism by regulating the tagatose pathway.

This study identifies RsaA sRNA's role in modulating antibiotic tolerance in S. aureus by affecting efflux pump expression and sensitivity to fluoroquinolone and beta-lactam antibiotics.

The paper shows that IsrR, an sRNA, controls aconitase expression in S. aureus during iron deficiency through a feedforward loop and aconitase's moonlighting activity regulates central metabolism.