Author

Michael R. DiGruccio

Washington University in St. LouisORCID 0000-0002-9375-2425Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Chen Kong· 1 shared David W. PistoniD· 1 shared Jeongmin LeeiD· 1 shared Xue Wen NgiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

Chen Kong

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1 paper

Recent·Most cited

Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans

Xue Wen Ng, Michael R. DiGruccio, Chen Kong, Jeongmin Lee, David W. Piston

This study shows that Complexin 2 inhibits glucagon and somatostatin secretion and disrupts paracrine inhibition of insulin secretion in pancreatic islets.

American Journal of Physiology-Endocrinology and Metabolism · Nov 10, 2025Peer-reviewedCell Biology