Author

Chen Kong

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

David W. PistoniD· 3 shared Jeongmin LeeiD· 2 shared Ahmed Shubbar· 1 shared Alessandro UstioneiD· 1 shared Daniel C. CastroiD· 1 shared Ian Miller· 1 shared Mahmoud MoradiiD· 1 shared Michael L. GrossiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBiophysics

David W. PistonORCID

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Author profile →

3 papers

Recent·Most cited

Dimer opening enables brain-type creatine kinase to sense membrane curvature

Samantha L. Gies, Nolan McLaughlin, Orianna H. Kou, Ahmed Shubbar, Chen Kong, Tianqi Wu, Sana Khan, Alessandro Ustione, Ian Miller, David W. Piston, Mahmoud Moradi, Michael L. Gross, Wade F. Zeno, Reza Dastvan

This study identifies dimer opening in CK-BB as a mechanism for sensing membrane curvature and regulating ATP regeneration under acidic conditions and substrate binding.

bioRxiv · Sep 22, 2026 · PreprintBiophysics

Role of Complexin 2 in the regulation of hormone secretion from the islet of Langerhans

Xue Wen Ng, Michael R. DiGruccio, Chen Kong, Jeongmin Lee, David W. Piston

This study shows that Complexin 2 inhibits glucagon and somatostatin secretion and disrupts paracrine inhibition of insulin secretion in pancreatic islets.

American Journal of Physiology-Endocrinology and Metabolism · Nov 10, 2025Peer-reviewedCell Biology

The role of mu-opioid receptors in pancreatic islet alpha cells

Chen Kong, Daniel C. Castro, Jeongmin Lee, David W. Piston

This study investigates the role of mu-opioid receptors in pancreatic islet alpha cells, showing they regulate glucagon secretion and are linked to metabolic disease.

bioRxiv · May 13, 2024 · PreprintPhysiology