Cancer BiologyScience AdvancesPeer-reviewed
Jagged1 regulates extracellular matrix deposition and remodeling in triple-negative breast cancer
Marjaana Parikainen, Ujjwal Suwal, Pekka Rappu…·Cecilia Sahlgren
This study shows Jagged1 promotes ECM remodeling in TNBC by enhancing fibroblast activation and TGFβ signaling, suggesting it as a therapeutic target.
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