Author

Mathew Sevao

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Jeffrey J. IliffiD· 2 shared Abigail G. SchindleriD· 1 shared Adisa KuburasiD· 1 shared Adriana Della PietraiD· 1 shared Alexandra B. PincusiD· 1 shared Allison J. SchaseriD· 1 shared Andrew F. RussoiD· 1 shared Caitlin S. LatimeriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Jeffrey J. IliffORCID

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2 papers

Recent·Most cited

Glymphatic function restored by α1-noradrenergic antagonism alleviates headache allodynia in mice

Adriana Della Pietra, Adisa Kuburas, Mathew Sevao, Tristen M. Castillo, Quinn Hanigan, Thomas L. Duong, Harold C. Flinn, Emilie H. Partridge, Murray A. Raskind, Jeffrey J. Iliff, Andrew F. Russo

This study shows that prazosin, an α1-noradrenergic antagonist, restores glymphatic function and reduces facial allodynia in mice with migraine-like symptoms.

bioRxiv · Apr 28, 2026 · PreprintNeuroscience

Aquaporin-4 mis-localization slows glymphatic clearance of α-synuclein and promotes α-synuclein pathology and aggregate propagation

Molly Braun, Matthew J. Simon, Jay Jang, Keith Sanderson, Justyna Swierz, Mathew Sevao, Alexandra B. Pincus, Allison J. Schaser, Jonathan E. Elliott, Miranda M. Lim, Vivek K. Unni, Abigail G. Schindler, Christopher Dirk Keene, Caitlin S. Latimer, Jeffrey J. Iliff

This study shows that AQP4 mis-localization impairs glymphatic clearance of α-synuclein and promotes its aggregation and spread in neurodegenerative diseases.

bioRxiv · Aug 14, 2024 · PreprintNeuroscience