Olga V. Razorenova

Population-associated molecular variation in histologically normal breast tissue is context-dependent and associated with distinct transcriptional states

The paper identifies context-dependent transcriptional states in normal breast tissue that show population-associated differences, with distinct biological programs in specific tissue contexts.

Coaching ribosome biogenesis from the nuclear periphery

This study shows that nuclear invaginations regulate ribosome biogenesis by contacting nucleoli, with high curvature increasing ribosome production and low curvature reducing it.