Author

Xiangfu Guo

Nanyang Technological University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Wenting ZhaoiD· 3 shared Xinwen Miao· 2 shared Yinyin ZhuangiD· 2 shared Aravind ChandrasekaraniD· 1 shared Changjin HuangiD· 1 shared Choon‐Peng ChngiD· 1 shared Christopher E. MilesiD· 1 shared Dahai LuoiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersBiophysics

Wenting ZhaoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Saddle Curvature Association of nsP1 Facilitates the Replication Complex Assembly of Chikungunya Virus in Cells

Xinwen Miao, Michelle Cheok Yien Law, Jatin Kumar, Choon‐Peng Chng, Yongpeng Zeng, Yaw Bia Tan, Jiawei Wu, Xiangfu Guo, Lizhen Huang, Yinyin Zhuang, Weibo Gao, Changjin Huang, Dahai Luo, Wenting Zhao

This study shows that Chikungunya virus nsP1 preferentially binds to positively curved membranes, enabling saddle curvature association critical for replication complex assembly.

Nature Communications · May 8, 2025Peer-reviewedBiophysics

Coaching ribosome biogenesis from the nuclear periphery

Yinyin Zhuang, Xiangfu Guo, Olga V. Razorenova, Christopher E. Miles, Wenting Zhao, Xiaoyu Shi

This study shows that nuclear invaginations regulate ribosome biogenesis by contacting nucleoli, with high curvature increasing ribosome production and low curvature reducing it.

bioRxiv · Jun 21, 2024 · PreprintCell Biology

Membrane curvature catalyzes actin nucleation through nano-scale condensation of N-WASP-FBP17

Kexin Zhu, Xiangfu Guo, Aravind Chandrasekaran, Xinwen Miao, Padmini Rangamani, Wenting Zhao, Yansong Miao

The paper demonstrates that membrane curvature catalyzes actin nucleation through the condensation and activation of N-WASP by FBP17, revealing a curvature-guided mechanism for actin remodeling.

bioRxiv · Apr 25, 2024 · PreprintMolecular Biology