Most High Throughput Expression Data Sets are Underpowered
Alexander J. Trostle, Jiasheng Wang, Lucian Li, Ying‐Wooi Wan, Zhandong Liu
The paper argues that high-throughput expression datasets are underpowered due to insufficient biological replicates and recommends at least six per condition to improve reliability.
bioRxiv · Aug 3, 2022 · PreprintBioinformatics