Author

Heike Kollmus

Helmholtz Centre for Infection ResearchORCID 0000-0002-9473-8676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Manuel ButtiniiD· 4 shared Pierre GarciaiD· 4 shared Alessandro MichelucciiD· 3 shared Klaus SchughartiD· 3 shared Lasse SinkkoneniD· 3 shared Mélanie H. ThomasiD· 3 shared Michel Guy André MittelbronniD· 3 shared Mona KaroutiD· 3 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Manuel ButtiniORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 30, 2020

Strain- and age-dependent features of the nigro-striatal circuit in three common laboratory mouse strains, C57BL/6J, A/J, and DBA/2J - Implications for Parkinson's disease modeling

Mélanie H. Thomas, Mona Karout, Beatriz Pardo Rodriguez…·Manuel Buttini

This study examines age-related changes in the nigro-striatal circuit across three mouse strains, revealing strain-specific differences in dopaminergic neuron integrity and highlighting the importance of considering strain and age in Parkinson's disease research.

1 citation

mousestatistical model

𝕏 PostBluesky

NeuroscienceMolecular NeurobiologyPeer-reviewedSep 30, 2020

A new synuclein-transgenic mouse model for early Parkinson's reveals molecular features of preclinical disease

Diana M. Hendrickx, Pierre Garcia, Amer Ashrafi…·Enrico Glaab

This study uses a synuclein-transgenic mouse model to identify molecular changes in early Parkinson's disease before neurodegeneration occurs.

10 citations

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsFrontiers in GeneticsPeer-reviewedSep 23, 2020

Pituitary Tumor Transforming Gene 1 orchestrates gene regulatory variation in mouse ventral midbrain during aging

Yujuan Gui, Mélanie H. Thomas, Pierre Garcia…·Lasse Sinkkonen

The paper identifies Pttg1 as a key regulator of gene expression variation in mouse ventral midbrain across aging, showing its role in transcriptome shifts and cell-type-specific changes.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 28, 2020

Quantitative trait locus mapping identifies Col4a6 as a novel regulator of striatal dopamine level and axonal branching in mice.

Mélanie H. Thomas, Yujuan Gui, Pierre Garcia…·Manuel Buttini

The paper identifies Col4a6 as a genetic regulator of striatal dopamine levels and axonal branching in mice through QTL mapping and RNA-seq analysis.

DOI 10.1101/2020.06.28.176206

mousebulk RNA-seq

𝕏 PostBluesky