A non-human primate model of Amyotrophic Lateral Sclerosis
Rachael HA Jones, Luciano Saieva, Fabien Balezeau, Ian Stephen Schofield, Caroline McCardle, Mark Baker, Stuart N. Baker
This study overexpresses TDP-43 in rhesus macaques to create an ALS model, showing motor neuron degeneration and widespread TDP-43 pathology.
bioRxiv · Oct 27, 2025 · PreprintNeuroscience