Dario Farina

Lateralised Transmission of Beta Oscillations From Cortex to Muscle During Movement Cancellation Reflects Selective Motor Inhibition

The paper examines beta oscillation transmission from cortex to muscle during movement cancellation, finding effector-specific peripheral synchronisation that reflects motor inhibition.

Probabilistic inference of Homonymous and Heteronymous Recurrent Inhibition in Human Muscles from Large-Scale Motor Neuron Recordings

The paper uses motor neuron recordings and simulation-based inference to estimate homonymous and heteronymous recurrent inhibition in human muscles during contractions.

Out-of-sight partners: autonomous wearable supernumerary limbs for dynamic co-manipulation

This study demonstrates that humans can effectively collaborate with autonomous wearable robotic limbs during dynamic tasks without visual feedback, achieving reliable task completion and high perceived safety.

An axonal sodium current gates motoneuron doublets and force amplification

The paper shows that axonal sodium currents drive doublets in motoneurons, amplifying force through nonlinear mechanisms, with neuromodulation affecting both timing and gain.

Neurofeedback Training on Motor Cancellation Enhances Peripheral but not Cortical Beta Band Oscillations

Mental Tasks Induce Common Modulations of Oscillations in Cortex and Spinal Cord

The paper shows mental tasks modulate cortical and spinal oscillations concurrently, with CST power in beta and low-gamma bands serving as a potential control signal for neural interfaces.

Unilateral resistance training induces greater rate coding adaptations in high-threshold motor units during maximal voluntary contractions

This study shows that unilateral resistance training increases maximal force through enhanced rate coding in high-threshold motor units during maximal voluntary contractions.

Validation of a multiscale Hill-type actuator against comprehensive benchmarks of motor unit and muscle force measurements

This paper develops and validates a multiscale Hill-type neuromuscular actuator against experimental benchmarks of motor unit and muscle force measurements, showing improved accuracy in force reproduction.

Neuromodulation enables transient flexible control of motoneurons

The paper shows that neuromodulation enables transient decorrelation of motoneurons with shared inputs, explaining flexible control through differential sensitivity to neuromodulation.

Spinal Motor Neuron Pools May be Partly Driven by Impulsive Common Inputs

This study shows that spinal motor neurons receive impulsive common inputs (iCI) that synchronize their activity and affect the transmission of continuous common inputs (cCI).

Rigid Control of Motor Unit Firing Rates in the Human Tibialis Anterior Muscle Persists during Neurofeedback

This study investigates whether human participants can voluntarily modulate motor unit firing rates in the tibialis anterior muscle during neurofeedback, finding limited flexibility consistent with rigid control.

High-frequency common inputs entrain motoneuron subpopulations differently

The paper shows that high-frequency common inputs affect motoneuron subpopulations differently, revealing frequency-dependent synchronization masked in whole-pool analyses.

TMS-Evoked Corticospinal Beta Oscillations in Humans Recorded from Muscles

This study shows that TMS-induced corticospinal beta oscillations can be detected in muscle recordings and share neural sources with endogenous beta rhythms.

Propagation of Beta bursts from the motor cortex to the motor units of multiple upper-limb muscles

This study demonstrates beta burst propagation from the motor cortex to upper-limb motor units using HDsEMG and EEG, showing time-locking and muscle-specific synchronisation.

Hill-type models of skeletal muscle and neuromuscular actuators: a systematic review

This paper reviews Hill-type muscle models, finding most lack innovation, proper validation, parameter identification, and reusability.

Projection of Cortical Beta Band Oscillations to a Motor Neuron Pool Across the Full Range of Recruitment

The paper investigates how cortical beta band oscillations are transmitted to motor neurons across different recruitment thresholds, finding uniform strength and consistent corticospinal delays.

Neural determinants of the increase in muscle strength and force steadiness of the untrained limb following a 4-week unilateral training

This study investigates neural adaptations in muscle strength and force steadiness in untrained limbs after unilateral training, finding reduced synaptic input variability and increased neural drive in trained and contralateral limbs.

NeuroNella: A Robust Unsupervised Algorithm for Identification of Neural Activity from Multielectrode Arrays

NeuroNella is an automated algorithm for identifying neuronal activity from multielectrode arrays, achieving less than 1% error rate in rodent and primate recordings.

Personalized mapping of inhibitory spinal cord circuits in vivo via non-invasive neural decoding and in silico modelling

This study uses high-density surface EMG and in silico modelling to reveal subject-specific inhibitory spinal microcircuit properties and control strategies.

Classification of motor-related brain states using high frequency information from muscle recordings

The paper classifies motor-related brain states using EMG and EEG frequency bands, finding comparable accuracy in decoding cancellation states from both modalities.

Flexible Control of Motor Units: Is the Multidimensionality of Motor Unit Manifolds a Sufficient Condition?

This study examines motor unit control flexibility by analyzing dimensionality of motor unit activity in two muscles, finding that while some muscles exhibit multidimensional manifolds, their control remains limited.

The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding

The paper analyzes motor unit firing rates during isometric contractions to show diverse rate coding patterns across motor unit pools.

I-Spin live: An open-source software based on blind-source separation for real-time decoding of motor unit activity in humans

The paper introduces an open-source software for real-time decoding of motor unit activity from EMG signals using blind-source separation, validated on synthetic and real data from human lower limb muscles.

The volitional control of individual motor units is constrained within low-dimensional neural manifolds by common inputs

This study investigates the dimensionality of motor unit control during isometric contractions, finding that motor units are constrained by common inputs and form synergistic groups.

Tutorial on MUedit: An open-source software for identifying and analysing the discharge timing of motor units from electromyographic signals

The paper introduces MUedit, an open-source software for decomposing EMG signals and analyzing motor unit discharge timing, with simulated and experimental data for benchmarking.

NeuroMechanics: Electrophysiological and Computational Methods to Accurately Estimate the Neural Drive to Muscles in Humans In Vivo

The paper describes new electrophysiological and computational methods to accurately estimate neural drive to muscles in humans in vivo by improving MU sampling and using data augmentation.

Wearable Neural Interfaces: Real-Time Identification of Motor Neuron Discharges in Dynamic Motor Tasks

This paper introduces an adaptive EMG decomposition algorithm for real-time motor neuron discharge identification during dynamic movements, showing improved performance in simulated and experimental data.

Larger and denser: an optimal design for surface grids of EMG electrodes to identify greater and more representative samples of motor units

This paper shows that larger and denser EMG electrode grids improve the identification of more representative motor unit samples through computational and experimental analysis.

Two motor neuron synergies, invariant across ankle joint angles, activate the triceps surae during plantarflexion

The paper identifies two motor neuron synergies in triceps surae muscles during plantarflexion that remain stable across ankle angles.

High-frequency cortical neural inputs to muscles during movement cancellation

This study investigates high-frequency cortical inputs to muscles during movement cancellation, finding increased beta and gamma oscillations in brain and muscle activity during NO-GO trials without behavioral changes.