NeurosciencebioRxivPreprint
A non-human primate model of Amyotrophic Lateral Sclerosis
Rachael HA Jones, Luciano Saieva, Fabien Balezeau…·Stuart N. Baker
This study overexpresses TDP-43 in rhesus macaques to create an ALS model, showing motor neuron degeneration and widespread TDP-43 pathology.
DOI 10.1101/2025.10.27.684759