Author
Newcastle UniversityORCID 0000-0002-1942-209XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Alexander Morris, Julia Hoopman, Vidhyadhar Nandana…·Lü Chen
The paper shows that SMN inactivation causes CB components to invade the nucleolus, suppressing rRNA production and telomerase function through altered condensate interactions.
Rachael HA Jones, Luciano Saieva, Fabien Balezeau…·Stuart N. Baker
This study overexpresses TDP-43 in rhesus macaques to create an ALS model, showing motor neuron degeneration and widespread TDP-43 pathology.
Enrico Pracucci, R. Graham, Laura Alberio…·Gian Michele Ratto
The paper shows that intracellular chloride levels in cortical pyramidal cells vary diurnally, affecting neuronal network stability and seizure latency.
Michael Briese, Nejc Haberman, Christopher R. Sibley…·Jernej Ule
The paper uses spliceosome iCLIP to map human spliceosome engagement with snRNAs and pre-mRNAs, identifying over 50,000 branchpoints and their associated splicing factor binding patterns.