FcεR1γ-based Activating Chimeric Antigen Receptors enhanced Natural Killer cell function against HLA-E+ cells
Lewis L. Lanier, John R. Greenland, Frank Momburg, Daniel R. Calabrese, Avishai Shemesh
This study modifies FcεR1γ with a 4-1BB co-stimulatory motif to enhance NK cell function against HLA-E+ cells, improving cytotoxicity in suppression-prone conditions.
The Journal of Immunology · Nov 2, 2025Peer-reviewedImmunology