Author

Alexandra N. Spirtos

The University of Texas Southwestern Medical CenterORCID 0000-0002-9487-4475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Cristel V. CamachoiD· 1 shared Jayanthi Sivasothy LeaiD· 1 shared Marwa W. AljardaliiD· 1 shared Sneh KouliD· 1 shared Sridevi ChallaiD· 1 shared W. Lee KrausiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Cristel V. CamachoORCID

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1 paper

Recent·Most cited

RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells

Alexandra N. Spirtos, Marwa W. Aljardali, Sridevi Challa, Sneh Koul, Jayanthi Sivasothy Lea, W. Lee Kraus, Cristel V. Camacho

This study shows that RBN-2397, a PARP7 inhibitor, reduces ovarian cancer cell proliferation and migration, and synergizes with paclitaxel to enhance these effects.

bioRxiv · Aug 20, 2024 · PreprintCancer Biology