ImmunologyCell ReportsPeer-reviewed
Lysosomal integrity suppresses TIR-1/SARM1 aggregation to restrain toxic propagation of p38 innate immunity
Samantha Y. Tse, Read Pukkila-Worley
The paper identifies lysosomal integrity as a regulator of TIR-1/SARM1 aggregation, preventing toxic p38 immune activation in C. elegans.
9 citations