Steffen Heyne

GraphClust2 improves RNA clustering and annotation by integrating sequence and structural data, revealing conserved structures in long non-coding RNAs and targets of Roquin-1.

CRUP predicts condition-specific regulatory units by analyzing histone modification ChIP-seq data and linking enhancers to target genes in rheumatoid arthritis.

snakePipes provides a flexible, scalable pipeline for integrative epigenomic analysis across multiple assays, simplifying reproducibility and extending existing studies.

This study identifies chromatin-state signatures linked to β-cell dysfunction and diabetes by combining epigenome mapping with single-cell transcriptomics in mice and humans.