Author

Lasse Højlund Eklund Thamdrup

Danish National Research FoundationORCID 0000-0002-9498-1529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2

Frequent Co-Authors

Anja BoiseniD· 2 shared Jan C. M. van HestiD· 2 shared Lars J. M. M. PaffeniD· 2 shared Matteo TollemetoiD· 2 shared Tania PatiñoiD· 2 shared Emily TsangiD· 1 shared Kurt V. GothelfiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

Anja BoisenORCID

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2 papers

Recent·Most cited

Enzyme-powered DNA origami nanostructures for enhanced mucosal diffusion

Matteo Tollemeto, Emily Tsang, Lars J. M. M. Paffen, Lasse Højlund Eklund Thamdrup, Jan C. M. van Hest, Tania Patiño, Kurt V. Gothelf, Anja Boisen

This study demonstrates DNA origami nanostructures that use enzymes to enhance mucosal diffusion, showing improved mobility in mucus through controlled enzyme placement.

Small Structures · Mar 1, 2026Peer-reviewedBioengineering

Topology Determines DNA Origami Diffusion in Intestinal Mucus

Matteo Tollemeto, Lars J. M. M. Paffen, Lasse Højlund Eklund Thamdrup, Anja Boisen, Jan C. M. van Hest, Tania Patiño

This study investigates how DNA origami nanoparticle shape and ligand patterning affect diffusion in intestinal mucus, finding that topology-specific optimization is crucial for mucus penetration.

Nano Letters · Aug 28, 2025Peer-reviewedBioengineering