Lars J. M. M. Paffen

This study demonstrates DNA origami nanostructures that use enzymes to enhance mucosal diffusion, showing improved mobility in mucus through controlled enzyme placement.

This paper uses machine learning to predict DNA origami stability in physiological conditions based on physicochemical parameters and DLS measurements.

This study investigates how DNA origami nanoparticle shape and ligand patterning affect diffusion in intestinal mucus, finding that topology-specific optimization is crucial for mucus penetration.

This study uses single particle tracking to analyze DNA origami interaction dynamics with cancer cells, revealing ligand-specific binding and density-dependent behavior.