Matteo Tollemeto

This study shows that mechanical flexibility improves DNA origami nanocarriers' transport through mucus by overcoming steric confinement, complementing surface passivation strategies.

This study demonstrates DNA origami nanostructures that use enzymes to enhance mucosal diffusion, showing improved mobility in mucus through controlled enzyme placement.

This paper uses machine learning to predict DNA origami stability in physiological conditions based on physicochemical parameters and DLS measurements.

This paper develops multilayer polymeric films for buccal delivery of GLP-1-RA and GDC, showing that triple-layer films provide sustained release and better mucosal compatibility than dual-layer films.

This study investigates how DNA origami nanoparticle shape and ligand patterning affect diffusion in intestinal mucus, finding that topology-specific optimization is crucial for mucus penetration.