Weihan Zhang

BioScientist Agent: Designing LLM-Biomedical Agents with KG-Augmented RL Reasoning Modules for Drug Repurposing and Mechanistic of Action Elucidation

The paper introduces BioScientist Agent, a framework combining a biomedical knowledge graph, variational graph auto-encoder, reinforcement learning, and LLMs to improve drug repurposing and mechanistic reasoning.

5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages

The paper analyzes 5-hydroxymethylcytosine in cell-free DNA to predict tumor types and stages with high accuracy.