Bin Liu

AttSiOff improves siRNA design by predicting inhibition and off-target effects using self-attention mechanisms, achieving better accuracy and generalization than existing methods.

DeepSipred predicts siRNA inhibition using sequence, thermodynamic, and expert knowledge features, achieving state-of-the-art performance on public datasets.

The paper identifies multiple regulatory sequences in the 3'-untranslated regions of mRNAs that control bloodstream-form-specific gene expression in Trypanosoma brucei.

The paper shows DRBD18 regulates RBP10 mRNA processing and export in Trypanosoma brucei by interacting with its 3-UTR, affecting mRNA stability and localization.

This study identifies ZC3H20 and ZC3H21 as mRNA stabilizing factors in Trypanosoma brucei, showing they regulate membrane and mitochondrial protein mRNAs during developmental transitions.

The paper analyzes 5-hydroxymethylcytosine in cell-free DNA to predict tumor types and stages with high accuracy.