Sophie Marianne Korn

The paper determines the structure of a plant-virus xrRNA and shows it forms a pseudoknot that confers exoribonuclease resistance, revealing a conserved mechanism across diverse viruses.

The paper shows that an A-T Hoogsteen base pair forms in naked DNA hairpins without protein binding, and identifies a DNA-specific motif stabilized by this pairing.

The paper shows Ku suppresses RNA-mediated innate immune responses in human cells, enabling primate-specific Alu element expansion by reducing dsRNA-induced inflammation.

This study defines Arid5a's DNA and RNA-binding preferences using biochemical and high-throughput methods, showing that disordered regions modulate its nucleic acid interactions and gene regulation.