Bei Liu

This paper identifies a U1-U3 snRNA-snoRNA interaction that links SF3B1 mutations to chromatin-state changes and genome instability, with therapeutic potential through antisense oligonucleotides.

The paper reveals an m6A-dependent mechanism where microRNAs bind chromatin-associated RNAs to activate transcription by recruiting chromatin remodelers and demethylases.

This study identifies FUBP1 as an Nm-binding protein and shows it regulates splicing by binding to Nm-modified intronic regions.

This study measures sequence-dependent A-T Hoogsteen dynamics in DNA using NMR, revealing distinct conformational specificity and sequence dependence.