Developmental BiologyStem Cell ReportsPeer-reviewed
Efficient RNA-mediated reprogramming of human somatic cells to naive pluripotency facilitated by tankyrase inhibition
Nicholas Bredenkamp, Jian Ping Yang, James Clarke…·Ge Guo
This paper demonstrates that tankyrase inhibition enables efficient, transgene-free reprogramming of human somatic cells to naive pluripotency, with clonal expansion and differentiation capabilities.
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