Cell BiologyCirculationPeer-reviewed
The Unique Role of Intracellular Perinuclear β-Adrenergic Receptors in defining Signaling Compartmentation and Pathological Cardiac Remodeling
Moriah Gildart Turcotte, Anne‐Maj Samuelsson, Sofia M. Possidento…·Kimberly L. Dodge‐Kafka
This study identifies Golgi-localized β-adrenergic receptors as critical for cAMP and calcium signaling, pathological gene transcription, and cardiomyocyte hypertrophy, offering a new therapeutic target for Dilated Cardiomyopathy.