Regulation of the Balance between Concentric and Eccentric Cardiac Hypertrophy by a CDC14A-KMT5A Signaling Pathway
Xueyi Li, Jinliang Li, Yuliang Tan, Anne‐Maj Samuelsson, Vi Bich Nguyen, Ramesh V. Nair, Anne‐Sophie Colombe, Dirk Grimm, Michael G. Rosenfeld, Michael S. Kapiloff
This paper identifies CDC14A and KMT5A as regulators of concentric vs. eccentric cardiac remodeling through epigenomic control of gene transcription, with CDC14A as a potential therapeutic target for heart failure.
bioRxiv · Feb 17, 2026 · PreprintCell Biology