Jinliang Li

This paper identifies CDC14A and KMT5A as regulators of concentric vs. eccentric cardiac remodeling through epigenomic control of gene transcription, with CDC14A as a potential therapeutic target for heart failure.

This study identifies Golgi-localized β-adrenergic receptors as critical for cAMP and calcium signaling, pathological gene transcription, and cardiomyocyte hypertrophy, offering a new therapeutic target for Dilated Cardiomyopathy.

This paper shows that targeting CIP4-CaNAβ2 signalosomes improves cardiac function and reduces remodeling after myocardial infarction in mice.

This study shows that FGF21-FGFR4 signaling in cardiac myocytes causes concentric hypertrophy in diabetic mice, suggesting it may contribute to HFpEF and that FGFR4 blockade could be a therapeutic target.