Mu‐Yun Wang

Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory

This study shows that specific Shank3 knockout in ventral CA1 neurons impairs social memory in mice, revealing a threshold for neuronal disruption required for this impairment.

Disrupted social memory ensembles in the ventral hippocampus underlie social amnesia in autism-associated Shank3 mutant mice

This study shows that disrupted social memory ensembles in the ventral hippocampus of Shank3 mutant mice correlate with impaired social behavior, suggesting a role in autism-associated social amnesia.