ImmunologybioRxivPreprint
Influenza A virus NS1 sequesters RNA:DNA hybrids to evade RNase H1-dependent innate immunity
Florence M. Kwaschik, Ian Pichler, José Luis Ruiz…·Benjamin G. Hale
DOI 10.64898/2026.05.04.722684
Author
Florence M. Kwaschik
University of ZurichORCID 0000-0002-9540-7991Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2023-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 19 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- MicrobiologyPLoS PathogensPeer-reviewed
TRIM28 is a target for paramyxovirus V proteins
Gauthier Lieber, Florence M. Kwaschik, Marie Lork…·Benjamin G. Hale
This paper shows that paramyxovirus V proteins interact with TRIM28, preventing its SUMO modification loss and ERE activation, thereby suppressing antiviral immune responses.
3 citations - ImmunologyEMBO ReportsPeer-reviewed
Influenza A Virus NS1 Limits Recognition of Double-Stranded Transposable Elements by Cytosolic RNA Sensors
Marie Lork, Liam Harold Childs, Gauthier Lieber…·Benjamin G. Hale
This study shows that IAV NS1 prevents cytosolic recognition of dsRNA from host transposable elements by binding to them, limiting innate immune activation.
8 citations